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DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is a homobifunctional crosslinker that is cell membrane permeable, with amine-reactive NHS esters at both ends of an 8-atom [11.4 angstrom] spacer arm for conjugating proteins, including intracellular proteins.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | $41 | In Stock | |
500 mg | $57 | In Stock | |
1 g | $74 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is a homobifunctional crosslinker that is cell membrane permeable, with amine-reactive NHS esters at both ends of an 8-atom [11.4 angstrom] spacer arm for conjugating proteins, including intracellular proteins. |
In vitro | ADCs consist of an antibody attached to an ADC cytotoxin through an ADC linker. |
Molecular Weight | 368.34 |
Formula | C16H20N2O8 |
Cas No. | 68528-80-3 |
Smiles | O(C(CCCCCCC(ON1C(=O)CCC1=O)=O)=O)N2C(=O)CCC2=O |
Relative Density. | 1.4 g/cm3 |
Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 10 mM | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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